[Biometry as a methodologic principle of clinical research in otorhinolaryngology]

The basic biometric theories for different types of clinical studies in Oto-Rhino-Laryngology are presented with a minimum use of formulae. A check-list is sketched with all points to be taken into account in the design of a study. The prerequisites for organisation of work and data processing are outlined. The understanding of this methodological basis can be very helpful in promoting the collaboration of clinicians and statisticians in pursuing successful clinical investigations in the field of Oto-Rhino-Laryngology.