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Bifascicular block in unexplained syncope is underrecognized and under-evaluated: A single-center audit of ESC
Muhammad Asim Shabbir1, Muhammad Hamza Saad Shaukat1, Moiz Ehtesham1
1Department of Internal Medicine, Albany Medical College, Albany, NY, United States of America.
Insights
Adherence to European Society of Cardiology guidelines for unexplained syncope with bifascicular block is low. Only 10.3% of patients received guideline-directed evaluation, highlighting a gap in care for complete heart block diagnosis.
Area of Science:
- Cardiology
- Electrophysiology
- Internal Medicine
Background:
- Bifascicular block on ECG can indicate complete heart block as a cause of unexplained syncope.
- European Society of Cardiology (ESC) guidelines recommend electrophysiology study (EPS) for diagnosis.
- Pacemaker (PPM) or implantable loop recorder (ILR) are indicated based on EPS results.
Purpose of the Study:
- To evaluate adherence to ESC guidelines for syncope with bifascicular block.
- To assess the rate of guideline-directed evaluation in hospitalized patients.
Main Methods:
- Retrospective audit of adult patients with bifascicular block and unexplained syncope.
- Inclusion criteria: unexplained syncope, bifascicular block, hospitalization (Jan 2018 - Aug 2019).
- Assessment of cardiology consults, EPS, ILR, and PPM offers.
Main Results:
- 11.2% of syncope admissions had bifascicular block; 5% had unexplained syncope.
- Cardiology consulted in 58.6% of cases; only 2 patients underwent EPS.
- Guideline-directed evaluation was performed in 10.3% of patients; no empiric PPM was given.
Conclusions:
- A minority of patients with unexplained syncope and bifascicular block receive guideline-directed evaluation.
- There is low adherence to ESC recommendations for syncope workup in this patient population.
Background:
The presence of bifascicular block on electrocardiography suggests that otherwise-unexplained syncope may be due to complete heart block. European Society of Cardiology (ESC) recommends investigating it with electrophysiology study (EPS). PPM is indicated if high-degree atrioventricular block is inducible. Long term rhythm monitoring with implantable loop recorder (ILR) is recommended if EPS is negative. We evaluated adherence to these guidelines.
Methods:
This is a single-center retrospective audit of adult patients with bifascicular block hospitalized for unexplained syncope between January 2018 and August 2019 under general medicine service. Patients with an alternative explanation for syncope were excluded. Guideline adherence was assessed by formal cardiology consult and whether EPS followed by ILR and/or PPM were offered.
Results:
65 out of 580 adult patients (11.2%) admitted to general medicine service for syncope had a bifascicular block; 29 (5%) were identified to have bifascicular block and unexplained syncope. Median age was 77 ±10 years; 9 (31%) were female, and 6 (20.7%) patients had at least one prior hospital visit for syncope at our academic medical center. Cardiology was consulted on 17 (58.6%) patients. Two patients were evaluated by EPS (1 refused) followed by ILR. Overall, 3 out of 29 patients (10.3%) received guideline-directed evaluation during the hospitalization based on ESC guidelines. None of the patients received empiric PPM during the index hospitalization.
Conclusion:
Among patients admitted to the general medicine service with unexplained syncope and bifascicular block, a minority (10.3%) underwent guideline-directed evaluation per ESC recommendations. Cardiology was consulted in 58.6% of cases.
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