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COVID-19 and myocarditis: a brief review
Fatma Taher1, Athar Eysa2, Dalia Fahmy3
1The College of Technological Innovation, Zayed University, 19282 Dubai, UAE.
Frontiers in Bioscience (Landmark Edition)
|February 28, 2022
Summary
COVID-19 infection can cause heart inflammation (myocarditis), but understanding and diagnosis remain challenging. This review analyzes case reports to clarify pathogenesis and evaluate diagnostic tests for better COVID-19 myocarditis management.
Area of Science:
- Cardiology
- Infectious Diseases
- Pathology
Background:
- COVID-19 viral infection is linked to cardiovascular complications, particularly myocarditis.
- The exact mechanisms and diagnostic protocols for COVID-19-related myocarditis are not well-established.
- Current understanding largely stems from limited case reports.
Purpose of the Study:
- To summarize theories on the pathogenesis of COVID-19-related myocarditis.
- To explore the diagnostic value of various clinical and imaging tests.
- To provide insights for improved clinical management strategies.
Main Methods:
- Systematic extraction of data from published case reports in the latter half of 2020.
- Review of diagnostic modalities including clinical evaluation, laboratory tests, ECG, echocardiography (ECHO), cardiac MRI, and endomyocardial biopsy.
- Synthesis of information regarding pathogenesis and diagnostic utility.
Main Results:
- Identified key theories explaining the development of myocarditis post-COVID-19 infection.
- Evaluated the contribution of different diagnostic tests in understanding the disease mechanism.
- Highlighted the importance of a multi-modal diagnostic approach.
Conclusions:
- A comprehensive understanding of COVID-19 myocarditis pathogenesis is emerging.
- Diagnostic tests play a crucial role in elucidating disease mechanisms and guiding treatment.
- Further research and standardized protocols are needed for optimal patient care.
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