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COVID-19 and myocarditis: a brief review

Fatma Taher1, Athar Eysa2, Dalia Fahmy3

  • 1The College of Technological Innovation, Zayed University, 19282 Dubai, UAE.

Frontiers in Bioscience (Landmark Edition)
|February 28, 2022
PubMed

Insights

COVID-19 infection can cause heart inflammation (myocarditis), but understanding and diagnosis remain challenging. This review analyzes case reports to clarify pathogenesis and evaluate diagnostic tests for better COVID-19 myocarditis management.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Pathology

Background:

  • COVID-19 viral infection is linked to cardiovascular complications, particularly myocarditis.
  • The exact mechanisms and diagnostic protocols for COVID-19-related myocarditis are not well-established.
  • Current understanding largely stems from limited case reports.

Purpose of the Study:

  • To summarize theories on the pathogenesis of COVID-19-related myocarditis.
  • To explore the diagnostic value of various clinical and imaging tests.
  • To provide insights for improved clinical management strategies.

Main Methods:

  • Systematic extraction of data from published case reports in the latter half of 2020.
  • Review of diagnostic modalities including clinical evaluation, laboratory tests, ECG, echocardiography (ECHO), cardiac MRI, and endomyocardial biopsy.
  • Synthesis of information regarding pathogenesis and diagnostic utility.

Main Results:

  • Identified key theories explaining the development of myocarditis post-COVID-19 infection.
  • Evaluated the contribution of different diagnostic tests in understanding the disease mechanism.
  • Highlighted the importance of a multi-modal diagnostic approach.

Conclusions:

  • A comprehensive understanding of COVID-19 myocarditis pathogenesis is emerging.
  • Diagnostic tests play a crucial role in elucidating disease mechanisms and guiding treatment.
  • Further research and standardized protocols are needed for optimal patient care.

Keywords:
COVID-19MyocarditisSARS-CoV-2

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