Maternal anemia and baby birth size mediate the association between short birth interval and under-five
Desalegn Markos Shifti1,2, Catherine Chojenta3, Elizabeth G Holliday4
1Saint Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia. desalegnmarkos@gmail.com.
Insights
Short birth intervals (less than 33 months) are linked to increased stunting and underweight in Ethiopian children. Maternal anemia and small birth size partially mediate these effects, highlighting key areas for intervention to reduce under-five undernutrition.
Area of Science:
- Public Health
- Pediatrics
- Maternal Health
Background:
- Inconclusive evidence exists on the association between short birth intervals and under-five undernutrition.
- Short birth interval is defined as a birth-to-birth interval of less than 33 months.
Purpose of the Study:
- To investigate the relationship between short birth interval and stunting, underweight, and wasting in Ethiopian children under five.
- To examine the potential mediating roles of maternal anemia and baby birth size in these associations.
Main Methods:
- Utilized data from the 2016 Ethiopia Demographic and Health Survey (EDHS).
- Employed Generalized Structural Equation Modeling (GSEM) to analyze associations and mediation effects.
- Outcome variables included stunting, underweight, and wasting among children under five.
Main Results:
- A significant association was found between short birth interval and stunting (AOR=1.49) and underweight (AOR=1.43).
- No significant association was observed between short birth interval and wasting (AOR=1.05).
- Maternal anemia and baby birth size significantly mediated the effects of short birth interval on stunting and underweight, accounting for 4.2% and 4.6% of the total effect, respectively.
Conclusions:
- Maternal anemia and small baby birth size are significant mediators in the link between short birth intervals and under-five undernutrition.
- Interventions to reduce under-five undernutrition in Ethiopia should address short birth intervals, maternal anemia, and small baby birth size.
Background:
Studies assessing the association between short birth interval, a birth-to-birth interval of less than 33 months, and under-five undernutrition have produced inconclusive results. This study aimed to assess the relationship between short birth interval and outcomes of stunting, underweight, and wasting among children aged under-five in Ethiopia, and potential mediation of any associations by maternal anemia and baby birth size.
Method:
Data from the 2016 Ethiopia Demographic and Health Survey (EDHS) was used. Stunting, wasting, and underweight among children aged under-five were outcome variables. Generalized Structural Equation Modeling (GSEM) was used to examine associations between short birth interval and outcomes, and to assess hypothesized mediation by maternal anemia and baby birth size.
Results:
Significant associations between short birth interval and stunting (AOR = 1.49; 95% CI = 1.35, 1.66) and underweight (AOR = 1.43; 95% CI = 1.28, 1.61) were found. There was no observed association between short birth interval and wasting (AOR = 1.05; 95% CI = 0.90, 1.23). Maternal anemia and baby birth size had a significant partial mediation effect on the association between short birth interval and stunting (the coefficient reduced from β = 0.337, p < 0.001 to β = 0.286, p < 0.001) and underweight (the coefficient reduced from β = 0.449, p < 0.001 to β = 0.338, p < 0.001). Maternal anemia and baby birth size mediated 4.2% and 4.6% of the total effect of short birth interval on stunting and underweight, respectively.
Conclusion:
Maternal anemia and baby birth size were identified as mediators of the association between short birth interval and under-five undernutrition status. Policies and programs targeting the reduction of under-five undernutrition should integrate strategies to reduce maternal anemia and small baby birth size in addition to short birth interval.
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