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Colon perforation after kidney transplantation.

S D Carson, R A Krom, K Uchida

    Annals of Surgery
    |July 1, 1978
    PubMed
    Summary

    Kidney transplant patients face a risk of colon perforation, often due to diverticulitis. Early surgical intervention, avoiding primary reanastomosis, improves survival rates for this serious complication.

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    Area of Science:

    • Gastroenterology
    • Transplant Surgery
    • Colorectal Surgery

    Background:

    • Colon perforation is a serious complication in kidney transplant recipients.
    • Diverticulitis is a primary cause of colon perforation in this patient population.

    Purpose of the Study:

    • To analyze the outcomes of colon perforation in kidney transplant patients.
    • To identify strategies for reducing mortality associated with this complication.

    Main Methods:

    • Retrospective analysis of kidney transplant patients who developed colon perforation between 1962 and 1977.
    • Evaluation of surgical management and outcomes, including survival rates.

    Main Results:

    • Approximately 2% of kidney transplant patients developed colon perforation.

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  • Diverticulitis was the most common cause (6/13 cases).
  • Survival beyond 90 days was poor (5/13) despite immunosuppression management.

    • Conclusions:

    • Early surgical intervention (exteriorization or resection without reanastomosis) can improve survival.
    • Prophylactic colon resection should be considered for transplant candidates with diverticulosis.
    • Aggressive investigation and treatment are crucial for transplant patients presenting with abdominal signs.