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Published on: August 2, 2017
Hypertensive disorders in pregnancy - Trends over eight years: A population-based cohort study
Dagmar Wertaschnigg1, Roshan J Selvaratnam2, Daniel L Rolnik3
1Department of Obstetrics and Gynaecology, School of Clinical Sciences, Monash University, Clayton, Victoria, Australia; Department of Obstetrics and Gynecology, Paracelsus Medical University, Salzburg, Austria.
Objective:
To describe the incidence and trends of hypertensive disorders of pregnancy and adverse pregnancy outcomes in recent years in Victoria, Australia.
Design:
Retrospective population-based cohort study, 2010 to 2017.
Setting:
State of Victoria, Australia.
Participants:
Population-based cohort study.
Main Outcome Measures:
Incidence of hypertensive disorders and its subtypes over time. Composite of major adverse maternal and perinatal outcome.
Results:
The incidence of hypertensive disorders (n = 36,406/614,524 pregnancies with 624,193 births) and all its subtypes has been stable, (n = 4,192/73,235 = 5.7% in 2010 to 4,601/78,576 = 5.9% in 2017). Compared to no hypertension, hypertensive disorders were associated with medically-initiated birth (aOR 4.70 [4.56, 4.84]), caesarean section (aOR 1.46 [1.43, 1.50]), placental abruption (aOR 1.94 [1.69, 2.22]), maternal intensive care or high-dependency unit admission (aOR 6.80 [6.45, 7.17]), composite of major adverse maternal outcome (aOR 3.87 [3.70, 4.04]), and composite of major adverse perinatal outcome (aOR 1.63 [1.56, 1.70]). The worst maternal and perinatal outcomes were among women with superimposed and early preterm preeclampsia.
Conclusion:
The incidence of all hypertensive disorders in pregnancy has remained stable over time. Early-onset preeclampsia and superimposed preeclampsia were most strongly associated with adverse pregnancy outcomes.
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