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A Rare Case of Granular Cell Tumor in the Right Upper Lung of an Adolescent Patient
John Grove1, Casey Meier1, Bahaaeldin Youssef2
1Pathology, Lincoln Memorial University-DeBusk College of Osteopathic Medicine, Knoxville, USA.
Abstract:
Granular cell tumors (GCTs) are rare neoplasms of neuroectodermal origin characterized by large polygonal cells with abundant eosinophilic and granular cytoplasm. GCTs rarely affect the lungs, with only a few cases reported in the literature. The pathophysiology of this Schwann cell-derived condition is not well understood but is thought to be due to recurring genetic mutations. GCTs have been linked with Noonan syndrome. Here, we report the case of a 17-year-old caucasian male who presented with partial upper airway obstruction due to a GCT. This case promotes awareness among pathologists and clinicians for this condition in the workup of patients presenting with upper airway obstruction.

