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Methanol Intoxication Presenting With Bilateral Optic Neuritis and Paracentral Acute Middle Maculopathy
Sherouk G Saad1, Yousef A Fouad2, Mohamed Nowara1
1Investigations Unit, Al Mashreq Eye Center, Cairo, EGY.
Methanol ingestion can cause vision loss due to optic nerve swelling and paracentral acute middle maculopathy (PAMM). Early macular assessment is crucial for managing methanol toxicity and its ischemic effects.
Area of Science:
- Ophthalmology
- Neurology
- Toxicology
Background:
- Accidental methanol ingestion can lead to severe visual impairment.
- Ophthalmic complications require multidisciplinary management.
Observation:
- A 52-year-old male presented with vision loss nine days after methanol ingestion.
- Ophthalmological evaluation revealed hand motion visual acuity and swollen optic discs.
- Macular OCT showed paracentral acute middle maculopathy (PAMM) in both eyes.
Findings:
- Brain MRI indicated ischemic insults.
- Steroid and antiplatelet therapy led to slight visual improvement.
- Bilateral optic atrophy developed within two months.
Implications:
- Methanol toxicity can cause ischemic maculopathy, not just optic nerve damage.
- Macular assessment is vital in cases of methanol intoxication.
- Prompt diagnosis and management are essential to mitigate vision loss.
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