Related Experiment Video
Updated: Oct 2, 2025

In vitro Assessment of Myocardial Protection following Hypothermia-Preconditioning in a Human Cardiac Myocytes Model
Published on: October 27, 2020
Iatrogenic Hypothermia during Hemodialysis Can Induce Serious Cardiac Arrhythmias in Diabetic Patient
Mohammed Sakr1, Abdullah K Alhwiesh2, Ali Alharbi1
1Diaverum Dialysis Center, King Fahd Hospital of the University, Al Khobar, Saudi Arabia.
Abstract:
Cardiovascular diseases are the main cause of morbidity and mortality in end-stage renal disease (ESRD) patients. Cardiac arrhythmias are prevalent in patients undergoing hemodialysis (HD), however, dialysis treatment per se can be considered as an arrhythmogenic stimulus. Uremic patients are characterized by a "pro-arrhythmic substrate" because of the high prevalence of ischemic heart disease, left ventricular hypertrophy, and autonomic neuropathy. The incidence of hypothermia in HD patient is unknown. The severity of hypothermia correlated to cardiac arrhythmias. Here, we report a 50-year-old Saudi lady known case of long-standing diabetes mellitus with diabetic retinopathy, nephropathy and neuropathy, ESRD on HD, coronary artery disease developed transient third-degree heart block secondary to iatrogenic hypothermia during HD session, which was completely resolved after adjusting temperature of dialysis machine. To the best of our knowledge, the association of third-degree atrioventricular block and hypothermia induced by HD session has not been previously reported.
Related Concept Videos
Hemodialysis II: Procedure and Complications
Hemodialysis III: Nursing Management
Dialysis
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Cardiac Catheterization I: Pre-Procedure Overview
Heart Failure Drugs: Diuretics
Hemodialysis I: Introduction

