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Updated: Oct 2, 2025

Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes
Published on: January 16, 2016
Exploring Helical Folding in Oligomers of Cyclopentane-Based ϵ-Amino Acids: A Computational Study
Hae Sook Park1, Young Kee Kang2
1Department of Nursing, Cheju Halla University, Cheju, 63092, Republic of Korea.
Abstract:
Invited for this month's cover picture is the group of Young Kee Kang at Chungbuk National University (Republic of Korea). The cover picture shows the preferred conformation of the hexamer of ϵ-amino acid Amc5 a with a cyclopentane substituent in the backbone investigated using DFT methods in chloroform and water. The Amc5 a hexamer adopted a stable left-handed conformation with a rise of 4.8 Å per turn both in chloroform and water. However, the hexamer of Ampa (an analogue of Amc5 a with replacing cyclopentane by pyrrolidine) adopted different conformations in chloroform and in water. Read the full text of their Research Article at 10.1002/open.202100253.
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