Related Experiment Video
Updated: Oct 2, 2025

Author Spotlight: Investigating the Tolerance of Cabbage Butterflies to Urban Pollutants
Published on: August 18, 2023
Occupational lead exposure is an independent modulator of hypertension and poor pulmonary function: A cross-sectional
Shiv K Yadav1, Gajanan P Patil1, Ankit Virmagami1
128993ICMR-National Institute of Occupational Health, Ahmedabad, GJ, India.
Abstract:
Blood lead level (BLL) is the primary biomarker for lead-exposure monitoring in occupationally exposed workers. We evaluated occupational lead-exposure (OE) impact on cardiopulmonary functions in lead-acid battery recycling unit workers. Seventy-six OE cases and 30 control subjects were enrolled for questionnaire-based socio-demographic, dietary, tobacco usage, and medical history data. Anthropometric measurements, systolic and diastolic blood pressure (SBP and DBP), and pulmonary function tests were performed. Venous blood was collected for BLL, hematological analysis, and biochemical analysis. OE caused a significant increase in BLL, SBP, DBP, and small airways obstruction in lung function tests. It also impaired platelet indices, affected renal and liver biochemical measurements, and promoted oxidative stress and DNA damage. Multilinear regression analysis suggested that BLL affected SBP (β = 0.314, p = .034) and increased small airways obstruction (FEV1/FVC, β = -0.37, p = .05; FEV25-75%, β = -0.351, p = .016). Higher BLL appears to be an independent modulator of hypertension and poor pulmonary function upon occupational lead exposure in lead-acid battery recyclers.
More Related Videos
Related Concept Videos
Types of Toxins
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
The Periodic Table and Organismal Elements
Periodic Table Provides Information...
Toxic Reactions: Overview
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
COPD: Management Using Bronchodilators and Corticosteroids
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation

