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Pellucid marginal corneal degeneration.

J H Krachmer

    Archives of Ophthalmology (Chicago, Ill. : 1960)
    |July 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Pellucid marginal degeneration is a rare, bilateral corneal thinning disorder. It is often misdiagnosed and requires differentiation from other noninflammatory and inflammatory peripheral corneal conditions.

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    Area of Science:

    • Ophthalmology
    • Corneal Diseases

    Background:

    • Pellucid marginal degeneration (PMD) is a bilateral, clear, inferior, peripheral corneal-thinning disorder.
    • It is characterized by corneal protrusion above a band of thinning, typically 1-2 mm from the limbus and 1-2 mm in width.
    • PMD is less familiar to American ophthalmologists due to predominantly European literature.

    Observation:

    • The abstract describes four cases of pellucid marginal degeneration.
    • The condition presents as a clear, inferior peripheral corneal thinning.
    • Corneal protrusion is observed above the thinned area.

    Findings:

    • Pellucid marginal degeneration is differentiated from noninflammatory corneal thinning disorders including keratoconus, keratoglobus, keratotorus, and posterior keratoconus.
    • It is also distinguished from inflammatory peripheral corneal disorders such as Terrien's peripheral corneal degeneration, Mooren's ulcers, and ulcers associated with connective tissue disease.

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    Implications:

    • Increased awareness of PMD among ophthalmologists is needed.
    • Accurate differentiation from other corneal conditions is crucial for appropriate patient management.
    • Further research and case studies can improve understanding and diagnosis of this rare disorder.