[Surgical antibiotic prophylaxis's usage review in a mother-child university hospital]

A Bleuse1, H Roy1, P Ovetchkine2

  • 1Unité de recherche en pratique pharmaceutique, département de pharmacie, CHU Sainte-Justine, 3175, chemin de la Côte Sainte-Catherine, H3T 1C5 Montréal, Québec, Canada.

Insights

Surgical antibiotic prophylaxis compliance was evaluated in pediatric patients. Key areas for improvement include standard order sets and preoperative timing to reduce surgical site infections.

Area of Science:

  • Infectious Diseases
  • Surgical Safety
  • Healthcare Quality Improvement

Context:

  • Pediatric surgical patients require standardized antibiotic prophylaxis protocols.
  • Compliance with current guidelines for surgical antibiotic prophylaxis is crucial for patient outcomes.
  • University hospitals face challenges in consistently implementing antibiotic prophylaxis protocols.

Purpose:

  • To assess compliance rates for surgical antibiotic prophylaxis in pediatric surgery.
  • To evaluate the effectiveness of tools aiding antibiotic prophylaxis prescription.
  • To determine the surgical site infection rate in pediatric surgical patients.

Summary:

  • A retrospective study of 125 pediatric surgical patients found an 87% compliance rate for surgical antibiotic prophylaxis indication.
  • Compliance with standard order sets (15%) and preoperative timing (30%) was suboptimal.
  • The surgical site infection rate was 4%, highlighting areas for protocol improvement.

Impact:

  • Suboptimal use of standard order sets and preoperative timing necessitates improved administrative tools and inter-departmental coordination.
  • Implementing a digital perioperative document is planned to enhance surgical antibiotic prophylaxis.
  • Improving compliance can lead to reduced surgical site infections and better patient safety in pediatric surgery.
Abstract

Related Concept Videos

Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy01:16

Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy

Helicobacter pylori, a resilient gram-negative bacterium, can thrive in the stomach's harsh, acidic environment. Infection with H. pylori leads to a cascade of events within the stomach lining. One of the critical disruptions caused by this bacterium is the interference with somatostatin production, a hormone responsible for regulating acid secretion. This interference tips the balance, escalating acid secretion and diminishing bicarbonate levels. This imbalance compromises the defensive...
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
Development of the Oral Microbiota01:28

Development of the Oral Microbiota

The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
Clinical Significance of Antibiotic Resistance01:25

Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...