COVID-19 Update for the GRAPPA 2021 Annual Meeting: Focus on COVID-19 Vaccination

Philip J Mease1, Kevin Winthrop2, Wendy Olsder3

  • 1P.J. Mease, MD, MACR, Rheumatology Research, Swedish Medical Center/Providence St. Joseph Health and University of Washington School of Medicine, Seattle, Washington, USA; pmease@philipmease.com.

Insights

COVID-19 vaccination is recommended for patients with autoimmune inflammatory diseases (AIRDs) on immunomodulatory therapy. Benefits of vaccination outweigh potential risks like flares or reduced efficacy, ensuring better protection against COVID-19.

Area of Science:

  • Rheumatology
  • Immunology
  • Infectious Diseases

Background:

  • Focus on COVID-19 vaccine efficacy and safety in patients with autoimmune inflammatory diseases (AIRDs) on immunomodulatory therapies.
  • Keynote address by Dr. Jeffrey Curtis (ACR COVID-19 Vaccine Clinical Guidance task force) discussed current knowledge gaps and guidance.
  • Addressed concerns from patient research partners regarding vaccine efficacy, safety, and medication management.

Framework:

  • Consensus: Vaccinate all AIRD patients as soon as eligible.
  • Vaccine benefits (protection against COVID-19) outweigh potential risks (flares, reduced efficacy).

Implementation:

  • Guidance on potential modification of immunomodulatory medication dosing for optimal vaccine response.
  • Discussion on managing vaccine hesitancy among social contacts and assessing vaccine efficacy.
  • Consideration of telehealth efficacy versus convenience for patient care.

Implications:

  • Ensures optimal COVID-19 protection for vulnerable AIRD patient population.
  • Provides evidence-based recommendations for clinicians managing AIRD patients.
  • Highlights the importance of patient-reported outcomes and concerns in vaccine guidance.

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