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Vitamin D supplementation: Pearls for practicing clinicians
1Endocrinology and Metabolism Institute, Cleveland Clinic, Cleveland, OH; Associate Professor of Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH willias9@ccf.org.
Vitamin D supplementation is widespread, but optimal repletion strategies for low 25-hydroxyvitamin D (25[OH]D) levels remain unclear. This review addresses assessment, counseling, and supplementation recommendations for vitamin D.
Area of Science:
- Endocrinology
- Nutritional Science
- Public Health
Background:
- Vitamin D deficiency is linked to numerous chronic diseases.
- Sun exposure's role in vitamin D levels is historically recognized.
- Widespread vitamin D supplementation necessitates clear guidance.
Purpose of the Study:
- To review the historical context of vitamin D.
- To examine methods for assessing and counseling patients on vitamin D use.
- To provide literature-based recommendations for vitamin D supplementation.
Main Methods:
- Literature review on vitamin D deficiency and supplementation.
- Analysis of current clinical practices and guidelines.
- Presentation of common clinical scenarios.
Main Results:
- Established benefits of vitamin D sufficiency are increasingly recognized.
- Uncertainty exists regarding optimal vitamin D repletion protocols.
- Potential hazards and long-term effects require further consideration.
Conclusions:
- Clear guidelines are needed for assessing and managing vitamin D levels.
- Patient counseling on vitamin D supplementation is crucial.
- Further research is warranted on optimal dosing and long-term safety.
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