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Describing a Transcription Factor Dependent Regulation of the MicroRNA Transcriptome
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Describing a Transcription Factor Dependent Regulation of the MicroRNA Transcriptome

Published on: June 15, 2016

Author Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based

Mathys Grapotte1,2,3, Manu Saraswat1,2, Chloé Bessière1,2

  • 1Institut de Biologie Computationnelle, Montpellier, France.

Nature Communications
|March 2, 2022
PubMed
Abstract

No abstract available in PubMed .

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Transcription Initiation01:47

Transcription Initiation

Initiation is the first step of transcription in eukaryotes. Prokaryotic RNA Polymerase (RNAP) can bind to the template DNA and start transcribing. On the other hand, transcription in eukaryotes requires additional proteins, called transcription factors, to first bind to the promoter region in the DNA template. This binding helps recruit the specific RNAP that can assemble on the DNA and start transcription.
The promoters and enhancers and their accessory proteins allow tight regulation of...

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