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Updated: Oct 1, 2025

Smartphone Fundus Photography
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Optimized hybrid machine learning approach for smartphone based diabetic retinopathy detection.

Shubhi Gupta1, Sanjeev Thakur2, Ashutosh Gupta3

  • 1Department of Computer Science, Amity University, Uttar Pradesh, India.

Multimedia Tools and Applications
|March 2, 2022
PubMed
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A new smartphone-based system offers an affordable and accessible method for detecting Diabetic Retinopathy (DR). This DIY approach utilizes advanced image processing and machine learning for early diagnosis, improving screening accessibility.

Area of Science:

  • Ophthalmology and medical imaging.
  • Biomedical engineering and computational health.

Background:

  • Diabetic Retinopathy (DR) is a diabetes complication damaging retinal blood vessels, often asymptomatic in early stages.
  • Yearly eye exams are crucial for early DR detection and effective treatment.
  • Traditional fundus cameras are costly and bulky, hindering widespread DR screening.

Purpose of the Study:

  • To develop and evaluate a low-cost, smartphone-based system for automated Diabetic Retinopathy detection and screening.
  • To create a DIY (do it yourself) retinal imaging solution using smartphone technology for accessible DR diagnosis.

Main Methods:

  • Smartphone-based retinal image acquisition using a DIY camera setup.
  • Image preprocessing including green channel transformation and Contrast Limited Adaptive Histogram Equalization (CLAHE).
Keywords:
And DIY smartphone enabled cameraDiabetic retinopathyMachine learningOptimizationSegmentationSmartphone

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  • Segmentation of optic disc (Watershed Transform) and abnormalities (Triplet Half Band Filter bank - THFB).
  • Feature extraction using Haralick and Anisotropic Dual Tree Complex Wavelet Transform (ADTCWT).
  • Optimal feature selection via Life Choice-Based Optimizer (LCBO) algorithm.
  • Classification using a hybrid Machine Learning (ML) model combining Neural Network (NN) and Deep Convolutional Neural Network (DCNN), optimized with Social Ski-Driver (SSD).
  • Main Results:

    • The proposed smartphone-based DR detection system demonstrated high accuracy on the APTOS-2019-Blindness-Detection and EyePacs datasets.
    • The system effectively categorized DR severity levels, including mild, moderate, severe, and proliferative DR, as well as normal cases.
    • Performance evaluation using various metrics confirmed the superiority of the proposed scheme compared to existing approaches.

    Conclusions:

    • Smartphone-based retinal imaging presents a viable, cost-effective alternative for DR screening.
    • The developed DIY system facilitates automated DR detection, enhancing accessibility for early diagnosis.
    • This technology holds significant potential for improving global eye health outcomes by enabling widespread DR screening.