Acute Myocarditis From the Use of Selective Androgen Receptor Modulator (SARM) RAD-140 (Testolone)

Area of Science:

• Endocrinology
• Cardiology
• Pharmacology

Background:

• Selective Androgen Receptor Modulators (SARMs) are compounds targeting androgen receptors.
• SARMs are investigated as potential therapies for conditions like hypogonadism.
• Their use for non-medical purposes, such as bodybuilding, is prevalent but unregulated.

Observation:

• A young male presented with symptoms suggestive of acute myocarditis.
• The patient reported recent self-medication with a SARM for bodybuilding purposes.
• This clinical presentation raised concerns about the cardiac safety of SARMs.

Findings:

• The case links SARM self-administration to a potential diagnosis of acute myocarditis.
• This suggests a possible adverse cardiovascular effect of SARMs when used without medical supervision.
• Further investigation into SARM-induced cardiotoxicity is warranted.

Implications:

• This case underscores the potential health risks associated with the non-prescribed use of SARMs.
• It highlights the need for increased awareness among athletes and bodybuilders regarding SARM dangers.
• Clinicians should consider SARM use when evaluating young individuals with unexplained cardiac events.