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Fc effector cross-reactivity: A hidden arsenal against SARS-CoV-2's evasive maneuvering

Michael W Grunst1, Pradeep D Uchil1

  • 1Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT 06510, USA.

Cell Reports. Medicine
|March 2, 2022
PubMed

It is unclear whether SARS-CoV-2 VOCs differentially escape Fc effector functions of antibodies in addition to neutralization. In this issue of Cell Reports Medicine, Richardson et al.1 show that VOCs differ both in their ability to evade as well as elicit cross-reactive Fc-effector functions.

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