Triphenylamine-based small-molecule fluorescent probes

Ammonia with the three hydrogens substituted by phenyls is known as triphenylamine (TPA), and is one of the most useful compounds because of its vast practical applications. Chemists have produced thousands of TPA derivatives to date. Because of its biocompatibility and structural features, it has been widely used in the fields of molecular recognition, molecular imaging, materials chemistry, and also in biology and medical science. Its strong electron-donating ability encourages scientists to produce different types of probes for molecular recognition. This review is based on recent developments and advances in TPA-based small molecular fluorescent probes within the time period 2010-2021. This extensive review may expedite improvements in more advanced fluorescent probes for vast and stimulating applications in the future.