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Updated: Oct 1, 2025

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Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae
Published on: February 24, 2023
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Stevens-Johnson Syndrome and Stroke Related to Mycoplasma
Sanjay K Yadava1, Soumya Adhikari1, Niranjan Ojha1
1Department of Internal Medicine, SUNY Upstate Medical University, Syracuse, NY, USA.
Summary
Mycoplasma pneumoniae can cause non-respiratory issues like skin problems and stroke. This case highlights a severe presentation including rash, mucositis, confusion, and ischemic stroke.
Area of Science:
- Infectious Diseases
- Neurology
- Dermatology
Background:
- Mycoplasma pneumoniae typically causes mild respiratory illness.
- Non-respiratory manifestations of Mycoplasma pneumoniae are increasingly recognized.
- These can involve multiple organ systems, including the skin, cardiovascular, and central nervous systems.
Observation:
- A 43-year-old male presented with a diffuse rash, severe mucositis, and confusion.
- The patient developed an ischemic stroke, a rare complication.
- This case underscores the diverse clinical spectrum of Mycoplasma pneumoniae infections.
Findings:
- The patient's symptoms were attributed to Mycoplasma pneumoniae infection.
- The presentation included Stevens-Johnson syndrome, a severe mucocutaneous reaction.
- Ischemic stroke was a significant neurological complication.
Implications:
- This case expands the understanding of Mycoplasma pneumoniae's extrapulmonary effects.
- It emphasizes the need for considering Mycoplasma pneumoniae in patients with unexplained mucocutaneous and neurological symptoms.
- Early diagnosis and treatment are crucial to prevent severe complications like stroke.
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