[Management of hyperuricemia in chronic kidney disease]
Nora Schwotzer1, Muriel Auberson2, Françoise Livio3
1Service de néphrologie et d'hypertension, Département de médecine, Centre hospitalier universitaire vaudois, 1011 Lausanne.
Abstract:
Hyperuricemia is often encountered as glomerular filtration rate decreased. It is associated with a more rapid decline of the renal function, but causality has not been demonstrated. Recent studies showed that treatment of hyperuricemia did not affect the progression in chronic kidney disease (CKD) patients. Thus, treatment with hypouricemic drugs of patients suffering of CKD and displaying asymptomatic hyperuricemia is not recommended. However, patients with CKD present often with acute flairs of gout, which might be difficult to treat. Therapeutic options are discussed in this article.
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