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Updated: Oct 1, 2025

Large-Scale SARS-CoV-2 Testing Utilizing Saliva and Transposition Sample Pooling
Published on: June 23, 2022
On an optimal testing strategy for workplace settings operating during the COVID-19 pandemic
1Instituto de Astronomia, Universidad Nacional Autónoma de México, CDMX, México.
This study presents an optimal SARS-CoV-2 testing strategy for workplaces to minimize infected-person-days (IPD). Even with limited daily testing (5-10% of staff), significant reductions in workplace infections are achievable.
Area of Science:
- Epidemiology
- Public Health
- Infectious Disease Control
Background:
- Daily SARS-CoV-2 testing is a standard workplace measure during the pandemic.
- Testing is often limited by cost, availability, and logistical challenges.
Purpose of the Study:
- To develop an optimal SARS-CoV-2 testing strategy for workplaces.
- To minimize the presence of pre-symptomatic and asymptomatic infected individuals.
Main Methods:
- Statistical modeling under simplifying assumptions.
- Numerical simulations to verify strategy robustness.
- Analysis of testing at 5% and 10% of the population daily.
Main Results:
- Significant reductions in infected-person-days (IPD) were demonstrated.
- A 30% IPD reduction was achieved with 5% daily testing.
- A 50% IPD reduction was achieved with 10% daily testing.
Conclusions:
- An optimized testing strategy can efficiently utilize limited SARS-CoV-2 testing resources.
- Workplace testing strategies can substantially decrease overall infection burden.
- This approach offers a robust method for managing workplace SARS-CoV-2 transmission.
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