Radionuclide localisation of parathyroid abnormality

There is much discussion about the ideal method for pre-operative localisation of parathyroid abnormality, ie, adenoma or hyperplasia, but as yet there is no simple and/or non-invasive screening method available. Different clinical centres have access to different imaging modalities and therefore use a variety of techniques ranging from ultrasound to direct venous sampling. This paper presents a version of a dual radionuclide computerised subtraction procedure, but the author wishes to point out that this technique is still undergoing research.