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Pathways to cures for multiple sclerosis: A research roadmap.

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A new roadmap outlines three pathways to cure Multiple Sclerosis (MS): stopping disease progression, restoring function, and preventing MS. This research plan aims to accelerate scientific breakthroughs for a cure.

Keywords:
Multiple sclerosisglobal healthknowledge gapspatient advocacyresearch priorities

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Area of Science:

  • Neuroimmunology
  • Regenerative Medicine
  • Preventive Neurology

Background:

  • Multiple Sclerosis (MS) affects nearly 3 million globally, with significant research progress but no cure.
  • The National MS Society is dedicated to finding cures for MS.

Purpose of the Study:

  • To present the Pathways to Cures Research Roadmap, detailing knowledge gaps, milestones, and priorities.
  • To recommend strategies for accelerating the development of Multiple Sclerosis cures.

Main Methods:

  • Developed through engagement with scientific leaders and individuals affected by MS.
  • Incorporated perspectives from over 300 people living with MS.
  • Endorsed by leading Multiple Sclerosis organizations.

Main Results:

  • The Roadmap identifies three interconnected pathways to cure MS: halting disease activity, restoring neurological function, and preventing new cases.
  • Recommendations include better global resource alignment on high-priority research.

Conclusions:

  • The developed Roadmap aims to foster collaboration and resource alignment for accelerated scientific breakthroughs.
  • This initiative seeks to expedite the achievement of cures for Multiple Sclerosis.