Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Biological Effects of Radiation02:59

Biological Effects of Radiation

16.2K
All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they...
16.2K
Imaging Studies for Cardiovascular System III: X-Ray01:20

Imaging Studies for Cardiovascular System III: X-Ray

308
The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
308
Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

77
Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
77
Myocarditis I: Introduction01:21

Myocarditis I: Introduction

52
Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
52
Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

69
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
69
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

47
Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
47

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Heart Substructure Radiation Dose and Cardiac Outcomes: Contemporary Evidence and Actionable Opportunities: JACC CardioOncology State-of-the-Art Review.

JACC. CardioOncology·2026
Same author

Design and Rationale of the REVEAL PET Study: A Study of <sup>124</sup>I-evuzamitide to Diagnose Cardiac Amyloidosis.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology·2026
Same author

Diagnostic Trends and Geographic Health Care Disparities Among Patients With Transthyretin Amyloid Cardiomyopathy.

Journal of the American Heart Association·2026
Same author

Chimeric antigen receptor T-cell therapy and cardiovascular outcomes in US Medicare beneficiaries.

European heart journal·2026
Same author

Association Between Regional Cardiac Radiation Dose and Magnetic Resonance Imaging Myocardial Contractility Parameters: A Prospective Pilot Study.

Tomography (Ann Arbor, Mich.)·2026
Same author

Correction: CPX-351 vs. conventional chemotherapy cardiotoxicity in high-risk AML: a post hoc phase III trial analysis.

Cardio-oncology (London, England)·2026
Same journal

Artificial intelligence-based prediction of transthoracic echocardiographic image quality in ICD/CRT-D candidates: A proof-of-concept study.

Kardiologia polska·2026
Same journal

Polish Heart Journal improves its standing: a record Impact Factor of 4.4.

Kardiologia polska·2026
Same journal

Giant coronary aneurysm associated with a coronary arteriovenous fistula treated by coil embolization.

Kardiologia polska·2026
Same journal

Targeting factor XI in left ventricular thrombus after myocardial infarction.

Kardiologia polska·2026
Same journal

Subthreshold orthostatic blood pressure reductions as a trigger of angina in advanced coronary artery disease: An N-of-1 observational analysis.

Kardiologia polska·2026
Same journal

Heart failure in a neonate with scimitar syndrome - successful treatment with percutaneous closure of large artery supplying pulmonary sequestration.

Kardiologia polska·2026
See all related articles

Related Experiment Video

Updated: Oct 1, 2025

Establishment of a Robust and Reproducible Model of Radiation-Induced Skin and Muscle Fibrosis
07:08

Establishment of a Robust and Reproducible Model of Radiation-Induced Skin and Muscle Fibrosis

Published on: August 31, 2022

1.8K

Radiation-induced cardiac dysfunction: Practical implications.

Lauren N Pedersen1, Walter Schiffer2, Joshua D Mitchell3,4,5

  • 1Department of Radiation Oncology, Washington University in St. Louis, St. Louis, MO, United States. cbergom@wustl.edu.

Kardiologia Polska
|March 3, 2022
PubMed
Summary
This summary is machine-generated.

Survivors of thoracic cancers treated with radiation therapy face risks of radiation-induced cardiac dysfunction. This review covers pathophysiology, risk factors, and management guidelines for cardiovascular healthcare providers.

Keywords:
cancercardio-oncologycardiovascular diseaseradiationradiation-induced cardiac dysfunction

More Related Videos

Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy
11:38

Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy

Published on: July 3, 2014

46.9K
Diffuse Optical Spectroscopy for the Quantitative Assessment of Acute Ionizing Radiation Induced Skin Toxicity Using a Mouse Model
06:21

Diffuse Optical Spectroscopy for the Quantitative Assessment of Acute Ionizing Radiation Induced Skin Toxicity Using a Mouse Model

Published on: May 27, 2016

8.3K

Related Experiment Videos

Last Updated: Oct 1, 2025

Establishment of a Robust and Reproducible Model of Radiation-Induced Skin and Muscle Fibrosis
07:08

Establishment of a Robust and Reproducible Model of Radiation-Induced Skin and Muscle Fibrosis

Published on: August 31, 2022

1.8K
Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy
11:38

Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy

Published on: July 3, 2014

46.9K
Diffuse Optical Spectroscopy for the Quantitative Assessment of Acute Ionizing Radiation Induced Skin Toxicity Using a Mouse Model
06:21

Diffuse Optical Spectroscopy for the Quantitative Assessment of Acute Ionizing Radiation Induced Skin Toxicity Using a Mouse Model

Published on: May 27, 2016

8.3K

Area of Science:

  • Cardiology
  • Oncology
  • Radiation Oncology

Background:

  • Radiation therapy for thoracic cancers can lead to cardiac dysfunction in survivors.
  • Despite advances, incidental heart radiation exposure remains a concern.
  • Early detection and management are crucial for patient outcomes.

Purpose of the Study:

  • To provide healthcare providers with foundational knowledge on radiation-induced cardiac pathophysiology.
  • To review advancements in radiation technology and their impact on cardiac health.
  • To detail current screening and management guidelines for at-risk patients.

Main Methods:

  • Literature review of radiation-induced cardiac pathophysiology.
  • Chronological review of radiation technology advancements.
  • Synthesis of treatment- and host-related risk factors.
  • Compilation of current screening and management guidelines.

Main Results:

  • Understanding radiation-induced cardiac pathophysiology is essential.
  • Treatment and host factors significantly influence cardiac dysfunction risk.
  • Established guidelines exist for screening and managing radiation-induced cardiac dysfunction.

Conclusions:

  • Cardiovascular healthcare providers must be equipped to manage radiation-induced cardiac dysfunction.
  • Proactive screening and management are vital for thoracic cancer survivors.
  • Continued research into cardiac-sparing techniques and long-term effects is necessary.