Related Experiment Video
Updated: Oct 1, 2025

Tissue Engineering by Intrinsic Vascularization in an In Vivo Tissue Engineering Chamber
Published on: May 30, 2016
Vascular Closure: the ABC's
Sukhdeep Bhogal1, Ron Waksman2
1Section of Interventional Cardiology, MedStar Washington Hospital Center, 110 Irving St.Suite 4B-1, Washington, NWDC, 20010, USA.
Vascular closure devices (VCDs) offer effective hemostasis for endovascular procedures, proving non-inferior to manual compression. These devices can reduce procedure time and costs while maintaining comparable complication rates.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Vascular Surgery
Background:
- Vascular access and closure are critical components of endovascular procedures.
- Access site-related complications independently predict adverse procedural outcomes.
Purpose of the Study:
- To review vascular closure methods, including manual compression and vascular closure devices (VCDs).
- To discuss VCD mechanisms, applications in arterial and venous arteriotomies, and associated complications.
Main Methods:
- Review of literature on vascular closure techniques and devices.
- Analysis of mechanisms of action for active and passive vascular closure devices.
- Examination of clinical outcomes and complication rates associated with different closure methods.
Main Results:
- Vascular closure devices (VCDs) have demonstrated non-inferiority compared to manual compression.
- VCDs reduce time to hemostasis, enabling early ambulation and discharge.
- Hospitalization costs may be reduced with VCD use, with comparable complication rates to manual compression.
Conclusions:
- Uncomplicated vascular closure is essential for preventing adverse procedural outcomes.
- VCDs facilitate faster patient recovery and potentially lower costs.
- Appropriate patient selection for VCDs is important, considering vascular anatomy.
More Related Videos
20:33A Case Series of Successful Abdominal Closure Utilizing a Novel Technique Combining a Mechanical Closure System with a Biologic Xenograft that Accelerates Wound Healing
Published on: July 4, 2019
09:52A Training and Testing System for Performing Vascular Reconstruction In Vitro
Published on: October 26, 2019