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Acute Pericarditis Leading to a Diagnosis of SLE: A Case Series of 3 Patients

Vishal K Narang1, Jonathan Bowen1, Omar Masarweh1

  • 1Kern Medical, Bakersfield, CA, USA.

Journal of Investigative Medicine High Impact Case Reports
|March 4, 2022
PubMed

Insights

Acute pericarditis is a rare presenting symptom of systemic lupus erythematosus (SLE). This case series highlights three patients diagnosed with SLE due to acute pericarditis, emphasizing the need for early diagnosis and treatment.

Area of Science:

  • Rheumatology
  • Cardiology

Background:

  • Cardiac involvement is common in systemic lupus erythematosus (SLE), affecting up to 50% of patients.
  • Acute pericarditis as the primary presenting symptom of SLE is uncommon, occurring in about 1% of cases.

Observation:

  • This case series details three patients with no prior SLE history who presented with acute pericarditis.
  • Acute pericarditis was the initial and leading manifestation leading to their SLE diagnosis.

Findings:

  • The patients initially received nonsteroidal anti-inflammatory drugs and colchicine for pericarditis.
  • Steroids and disease-modifying anti-rheumatologic agents were eventually required for SLE management.

Implications:

  • Highlights the importance of considering SLE in patients presenting with acute pericarditis, even without a prior history.
  • Suggests that prompt diagnosis and appropriate immunosuppressive therapy are crucial for managing SLE presenting with cardiac symptoms.

Keywords:
Systemic lupus erythematosuspericarditis

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