Related Experiment Video
Updated: Oct 1, 2025

Guidelines for Elective Pediatric Fiberoptic Intubation
Published on: January 17, 2011
Pediatric suicides reported to U.S. poison centers.
Jennifer A Ross1, Molly H Woodfin1, Saumitra V Rege1
1Division of Medical Toxicology, Department of Emergency Medicine, University of Virginia School of Medicine, Charlottesville, VA, USA.
The rate of pediatric suicide-related self-poisoning cases has significantly increased, particularly in younger children aged 10-12. Over-the-counter medications like acetaminophen are frequently used in these incidents.
Area of Science:
- Pediatric mental health
- Toxicology
- Public health
Background:
- The pediatric mental health crisis is escalating, leading to a rise in adolescent suicide-related incidents.
- Self-poisoning among adolescents is a growing concern, with increasing cases reported.
Purpose of the Study:
- To analyze trends in pediatric suspected suicides between 2015 and 2020.
- To identify age groups and substances most affected by the rise in self-poisoning.
Main Methods:
- Data from the National Poison Data System was analyzed.
- Trends in rates and frequencies of pediatric suspected suicides were examined from 2015 to 2020.
Main Results:
- Over 514,000 pediatric suspected suicides were analyzed.
- The highest increase in suspected suicides was observed in children aged 10-12 (109.3%).
- Acetaminophen and ibuprofen were the most common substances, with acetaminophen showing the largest increase in exposure rates.
Conclusions:
- The findings indicate a worsening pediatric mental health crisis extending to younger populations.
- Easier access to over-the-counter medications may contribute to their use in pediatric self-poisoning.
- Mental health screenings and interventions are crucial for preventing further increases in self-poisoning cases.
Related Concept Videos
Anticholinesterase Agents: Poisoning and Treatment
Irreversible agents form a strong bond with the cholinesterase enzyme, making it inactive. The breakdown of the phosphorylated enzyme is...
Prevention of Further Absorption of Poison
Pharmacovigilance
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
Nonlinear Pharmacokinetics: Dependence of Elimination Half-Life and Dose Clearance
A study on guinea pigs examined the...
Types of Toxins
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
Enhanced Elimination of Poison
Antidotes serve a crucial role in counteracting the effects of poison by inhibiting enzymes responsible for producing harmful drug metabolites. In some cases, these toxic metabolites can be neutralized by endogenous cosubstrates, which are maintained at specific concentrations to prevent interaction with cellular macromolecules and subsequent cell death.
Renal excretion is the...

