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Scedosporium apiospermium keratitis: a case report
1Faculty of Medicine Department of Ophthalmology, Suleyman Demirel University, Isparta, Turkey. drumutkaraca@gmail.com.
Journal of Medical Case Reports
|March 4, 2022
Summary
Scedosporium apiospermum keratitis is a rare fungal eye infection. This case highlights challenges in diagnosis and treatment, emphasizing penetrating keratoplasty for resistant infections.
Area of Science:
- Ophthalmology
- Mycology
- Infectious Diseases
Background:
- Scedosporium apiospermum is an opportunistic filamentous fungus causing rare ocular infections.
- Fungal keratitis presents diagnostic and therapeutic challenges, particularly in non-resolving cases.
Observation:
- A 30-year-old farmer with contact lens misuse developed severe Scedosporium apiospermum keratitis.
- Spectrophotometric analysis confirmed S. apiospermum; the patient showed resistance to fluconazole and amphotericin B, and unresponsiveness to voriconazole.
Findings:
- Therapeutic penetrating keratoplasty was successful in treating the severe fungal keratitis.
- Antifungal drug resistance complicated the management of this S. apiospermum infection.
Implications:
- S. apiospermum keratitis should be considered in patients with ocular trauma or contact lens use, especially those unresponsive to standard treatments.
- This case underscores the importance of considering fungal etiologies in refractory keratitis and highlights the role of surgical intervention.
