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Updated: Oct 1, 2025

Rejection of Fluorescence Background in Resonance and Spontaneous Raman Microspectroscopy
Published on: May 18, 2011
Comment on "Finding reduced Raman spectroscopy fingerprint of skin samples for melanoma diagnosis through machine
Ivan A Bratchenko1, Lyudmila A Bratchenko1
1Laser and Biotechnical Systems Department, Samara National Research University, Moskovskoe shosse 34, Samara 443086, Russia.
Abstract:
This paper comments on the article "Finding reduced Raman spectroscopy fingerprint of skin samples for melanoma diagnosis through machine learning" by D. C. Araújo et al. The authors apply Raman spectroscopy for the classification of benign and malignant skin neoplasms based on their Raman spectra. Despite the high performance of the proposed technique it may provide unreasonably high accuracy because of incorrect cross-validation procedure. To confirm the possibility to discriminate neoplasm skin tissues based on Raman spectra analysis the authors should provide additional data regarding utilized cross-validation procedure.
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