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Acceleration of Brain Susceptibility-Weighted Imaging with Compressed Sensitivity Encoding: A Prospective Multicenter
1From the Department of Radiology (J.D., Y.D., Z.Z., L.G., F.Z., R.C., Y.L.), Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
AJNR. American Journal of Neuroradiology
|March 4, 2022
Summary
Compressed sensitivity encoding (CS) accelerates brain SWI scans, reducing time significantly. CS factor 4 is recommended for routine use, while CS factor 10 offers fast detection of abnormalities but sacrifices visualization of certain brain structures.
Area of Science:
- Neuroimaging
- Magnetic Resonance Imaging (MRI)
Background:
- Three-dimensional susceptibility-weighted imaging (SWI) is crucial for neuroimaging but suffers from long scan times.
- Fast imaging techniques are needed for clinical validation of SWI.
Purpose of the Study:
- To evaluate brain SWI accelerated by compressed sensitivity encoding (CS).
- To identify optimal CS acceleration factors for clinical practice.
Main Methods:
- Ninety-nine subjects underwent 8 SWI sequences with varying CS and sensitivity encoding (SE) acceleration factors.
- Quantitative (SNR, contrast ratio) and subjective (image quality, visibility, diagnostic confidence) assessments were performed.
Main Results:
- CS significantly reduced scan time (202s to 41s) with acceleration up to factor 10.
- SNR, contrast ratio, and visual scores decreased with higher CS factors.
- Substantia nigra-red nucleus and internal cerebral vein visibility became unacceptable at CS6-CS10.
- Basilar artery and various intracranial diseases (microbleeds, cavernomas, gliomas, venous malformations, hemorrhage) were well-diagnosed across CS sequences.
Conclusions:
- CS factor 4 is recommended for routine clinical practice.
- CS factor 10 is a potential fast surrogate for detecting susceptibility-related abnormalities and basilar artery visualization, despite sacrificing substantia nigra-red nucleus and internal cerebral vein visibility.
