Related Experiment Video

Updated: Oct 1, 2025

Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model
03:45

Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model

Published on: August 8, 2022

3.8K

Emergency department utilization in patients with hypertrophic cardiomyopathy: a nationwide population-based study

You-Jung Choi1, Bongseong Kim2, Hyun-Jung Lee1

  • 1Cardiac Diagnostic Test Unit, Section of Cardiovascular Imaging, Division of Cardiology, Cardiovascular Center, Department of Internal Medicine, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Korea.

Scientific Reports
|March 4, 2022
PubMed

Insights

Hypertrophic cardiomyopathy (HCM) patients frequently visit emergency departments (EDs), primarily for cardiovascular issues. These ED visits are linked to increased hospitalizations and mortality within 90 days.

Area of Science:

  • Cardiology
  • Public Health
  • Health Services Research

Background:

  • Hypertrophic cardiomyopathy (HCM) poses a growing healthcare challenge.
  • Limited data exists on emergency department (ED) utilization patterns for HCM patients.

Purpose of the Study:

  • To investigate the characteristics and outcomes of emergency department (ED) utilization among a nationwide cohort of hypertrophic cardiomyopathy (HCM) patients.
  • To identify the primary reasons for ED visits and associated clinical outcomes.

Main Methods:

  • A nationwide population-based study utilizing data from the National Health Insurance Service database (2015-2016).
  • Inclusion of 14,542 patients diagnosed with hypertrophic cardiomyopathy (HCM).
  • Analysis of ED utilization, primary discharge diagnoses, hospitalizations, and all-cause mortality within 90 days post-ED visit.

Main Results:

  • 22.1% of HCM patients utilized ED services within one year.
  • Cardiovascular diseases were the most frequent reason for ED visits (41.5%).
  • HCM patients visiting the ED experienced higher rates of hospitalization (37.2%) and 90-day all-cause mortality (7.2%).
  • ED visits for cardiovascular disease significantly increased the risk of 90-day all-cause mortality (aOR, 2.72).

Conclusions:

  • Emergency department utilization is substantial among hypertrophic cardiomyopathy patients.
  • Cardiovascular conditions are the leading cause of ED visits in this population.
  • ED visits are associated with significant morbidity and mortality, highlighting the need for improved management strategies and healthcare policies for HCM.

More Related Videos

Scanning Electron Microscopy of Macerated Tissue to Visualize the Extracellular Matrix10:21

Scanning Electron Microscopy of Macerated Tissue to Visualize the Extracellular Matrix

Published on: June 14, 2016

10.2K
An Approach to Study Shape-Dependent Transcriptomics at a Single Cell Level06:02

An Approach to Study Shape-Dependent Transcriptomics at a Single Cell Level

Published on: November 2, 2020

5.8K

Related Concept Videos

Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
78
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
55
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
47
Cardiomyopathy I: Introduction and Classification01:25

Cardiomyopathy I: Introduction and Classification

Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
99
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
85
Heart Failure V: Medical Management01:30

Heart Failure V: Medical Management

Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...
37