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Metastatic neuroendocrine tumors mimicking as primary ocular disease
Alice Shen1, Arezu Haghighi1, Tom Liang1
1Los Angeles County + University of Southern California Medical Center, Department of Ophthalmology, 2051 Marengo St, Los Angeles, CA, 90033, USA.
Purpose:
To report two cases of metastatic neuroendocrine tumors masquerading as primary ocular disease.
Observations:
Case 1 is a 38-year-old man who was referred with subacute onset diplopia and fluctuating ptosis suggestive of myasthenia gravis. Case 2 is a 21-year-old man who presented with blurry vision and was found to have a pigmented ciliary body mass and retinal detachment suggestive of uveal melanoma. Both patients were ultimately diagnosed with metastatic neuroendocrine tumors.
Conclusions And Importance:
Neuroendocrine tumors, though rare and infrequently metastatic to the eye and orbit, can initially present with ocular signs. A broad differential and careful consideration of ocular and systemic symptoms are critical in such challenging cases.
