Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Bidirectional associations between cannabis use, oddball performance and P3 event-related potential.

medRxiv : the preprint server for health sciences·2026
Same author

Untangling relationships between cognitive development and child and adolescent mental health: Findings from the ABCD Study.

Developmental cognitive neuroscience·2026
Same author

The 10-year stability of three subscale scores of the Self-Report of the Effects of Alcohol measure and their relationship to changes in drinking quantities over the same period.

Alcohol, clinical & experimental research·2026
Same author

What we have learned about adolescent mental health and where we are going after a decade with the Adolescent Brain Cognitive Development Study.

Developmental cognitive neuroscience·2026
Same author

Hippocampal volumes in UK Biobank are associated with <i>APOE</i> only in older adults.

Alzheimer's & dementia (Amsterdam, Netherlands)·2024
Same author

Alcohol, smoking, and brain structure: common or substance specific associations.

medRxiv : the preprint server for health sciences·2024

Related Experiment Video

Updated: Oct 1, 2025

Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia
13:08

Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia

Published on: December 2, 2015

9.1K

Reliability and stability challenges in ABCD task fMRI data.

James T Kennedy1, Michael P Harms1, Ozlem Korucuoglu1

  • 1Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, United States.

Neuroimage
|March 4, 2022
PubMed
Summary
This summary is machine-generated.

Task-based functional MRI (fMRI) in children shows poor reliability and long-term stability for measuring brain activation. This impacts the ability to link brain activity to behavior, highlighting a need for improved methods.

More Related Videos

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
09:14

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Published on: March 14, 2025

384
Correlating Behavioral Responses to fMRI Signals from Human Prefrontal Cortex: Examining Cognitive Processes Using Task Analysis
10:33

Correlating Behavioral Responses to fMRI Signals from Human Prefrontal Cortex: Examining Cognitive Processes Using Task Analysis

Published on: June 20, 2012

12.9K

Related Experiment Videos

Last Updated: Oct 1, 2025

Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia
13:08

Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia

Published on: December 2, 2015

9.1K
Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
09:14

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Published on: March 14, 2025

384
Correlating Behavioral Responses to fMRI Signals from Human Prefrontal Cortex: Examining Cognitive Processes Using Task Analysis
10:33

Correlating Behavioral Responses to fMRI Signals from Human Prefrontal Cortex: Examining Cognitive Processes Using Task Analysis

Published on: June 20, 2012

12.9K

Area of Science:

  • Neuroscience
  • Cognitive Science
  • Developmental Psychology

Background:

  • Trait stability is crucial for individual differences research using functional MRI (fMRI).
  • Previous studies in adults questioned the trait stability of task-fMRI measures.
  • Limited knowledge exists regarding task-fMRI trait stability in children.

Purpose of the Study:

  • To examine the within-session reliability and long-term stability of individual differences in task-fMRI measures in children.
  • To evaluate factors influencing reliability and stability, such as motion.
  • To assess the utility of fMRI data for brain-behavior associations in pediatric populations.

Main Methods:

  • Utilized fMRI data from the Adolescent Brain Cognitive Development (ABCD) Study Release v4.0.
  • Analyzed regional brain activation during tasks assessing reward processing, response inhibition, and working memory.
  • Quantified reliability and stability as the ratio of stable variance to total variance, considering motion effects.

Main Results:

  • Reliability and stability were poor across most brain regions, with average values of 0.088 (within-session) and 0.072 (long-term).
  • Few regions exceeded a 'poor' cut-off of 0.4, with only 4.9% exceeding 0.2.
  • Participant motion significantly impacted reliability and stability, with lower motion correlating with higher (though still poor) values.

Conclusions:

  • Task-fMRI measures in children exhibit poor reliability and long-term stability, limiting their utility for individual differences research.
  • The low stability drastically reduces statistical power for detecting brain-behavior associations.
  • Optimization of task design, scanning parameters, and data processing is urgently needed to improve fMRI data quality in children.