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An update on radiomics techniques in primary liver cancers
Vincenza Granata1, Roberta Fusco2, Sergio Venazio Setola3
1Division of Radiology, "Istituto Nazionale Tumori IRCCS Fondazione Pascale - IRCCS di Napoli", Via Mariano Semmola 80131, Naples, Italy. v.granata@istitutotumori.na.it.
Infectious Agents and Cancer
|March 5, 2022
Summary
Radiomics, extracting quantitative data from medical images, shows promise for liver cancer monitoring. However, standardization issues hinder its widespread clinical adoption.
Area of Science:
- Radiology
- Oncology
- Medical Imaging Analysis
Background:
- Radiomics extracts quantitative metrics from medical images, revealing tissue characteristics like heterogeneity.
- These features can aid clinical decision-making when combined with other patient data.
Purpose of the Study:
- To provide a narrative review of radiomics in primary liver cancers.
- To discuss current limitations and future perspectives of radiomics in this field.
Main Methods:
- This study is a narrative review.
- Focuses on radiomics applications in primary liver cancers, including hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC).
Main Results:
- Radiomics can support cancer detection, diagnosis, prognosis assessment, and treatment response evaluation.
- It offers a repeatable tool for monitoring disease status in HCC and ICC patients.
Conclusions:
- Radiomics shows promise for liver cancer management but lacks standardization and generalization.
- Key limitations include data quality, repeatability, reproducibility, and model overfitting, restricting clinical translation.
