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MicroRNA-based Regulation of Picornavirus Tropism
Published on: February 6, 2017
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Cross-species microRNA transmission modulates flavivirus growth in mosquitoes
Shwetha Shivaprasad1, Peter Sarnow1
1Department of Microbiology & Immunology, Stanford University SOM, Stanford, CA 94305, USA.
Trends in Parasitology
|March 5, 2022
Abstract:
Mosquitoes can be infected with a variety of RNA viruses. Recently,Zhu et al. demonstrated that human microRNA hsa-miR-150-5p is acquired by mosquitoes during blood meals and protects the Dengue virus by downregulation of chymotrypsin AaCT-1 mRNA. This finding suggests the use of microRNA antagomirs as an antiviral approach in mosquitoes.
