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Related Experiment Video

Updated: Oct 1, 2025

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

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Cryptogenic, Embolic Stroke-Looking Backstage.

Prof James Ker¹

¹Department of Internal Medicine, University of Pretoria, Pretoria, South Africa.

Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association

|March 5, 2022

Summary

This case report details a rare pulmonary venous thrombosis linked to COVID-19, causing embolic stroke. It highlights pulmonary veins as a potential source of arterial thromboembolism, necessitating thorough assessment.

Keywords:

COVID 19 Embolic Pulmonary veins Stroke Thrombosis

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Area of Science:

Cardiology and Neurology
Infectious Diseases

Background:

Stroke is a leading cause of disability and death, often resulting from thromboembolism originating in the left atrium, ventricle, or valves.
Pulmonary venous thrombosis is an exceedingly rare condition, with limited reported cases.

Observation:

This case report presents a patient experiencing an embolic stroke.
The identified source of the thrombus was the left inferior pulmonary vein.
The condition was associated with a recent COVID-19 infection.

Findings:

This represents the fourth documented case of pulmonary venous thrombosis attributed to COVID-19.
The findings indicate that pulmonary veins, not just the left atrium, can be the proximal origin of arterial thromboembolism.

Implications:

The study suggests that pulmonary veins should be routinely assessed in all patients presenting with arterial thromboembolism.
This underscores the need to consider unusual sources of embolism in the context of viral infections like COVID-19.
Enhanced diagnostic evaluation of pulmonary veins may improve stroke etiology identification and patient management.