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Long noncoding RNA SNHG17: a novel molecule in human cancers
1Cancer Medical Center, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, 210011, Jiangsu, China.
Cancer Cell International
|March 6, 2022
Summary
Small nucleolar RNA host gene 17 (SNHG17) is a novel long non-coding RNA (lncRNA) implicated in various cancers. This review explores SNHG17
Area of Science:
- Molecular Biology
- Oncology
- Genetics
Background:
- Long non-coding RNAs (lncRNAs) are increasingly recognized for their roles in disease pathogenesis.
- Dysregulation of lncRNAs is a common feature in various human cancers.
- Small nucleolar RNA host gene 17 (SNHG17) is an emerging lncRNA associated with oncogenic functions.
Purpose of the Study:
- To review and summarize current research on the biological functions of SNHG17.
- To discuss the potential clinical applications of SNHG17 in cancer diagnosis and treatment.
- To highlight the oncogenic roles of SNHG17 in tumor progression.
Main Methods:
- Literature review of studies investigating SNHG17.
- Analysis of research on SNHG17's involvement in cancer cell proliferation, migration, and invasion.
- Examination of studies on SNHG17's association with apoptosis and drug resistance.
Main Results:
- SNHG17 is highly expressed in numerous tumor types.
- SNHG17 influences key cancer cell behaviors including proliferation, migration, invasion, and apoptosis.
- Elevated SNHG17 expression correlates with poor clinical prognosis and chemoresistance.
Conclusions:
- SNHG17 plays a significant role in cancer development and progression.
- SNHG17 holds promise as a potential biomarker for cancer prognosis.
- Targeting SNHG17 may offer novel therapeutic strategies for cancer treatment.
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