Racial/ethnic differences persist in treatment choice and outcomes in isolated intervention for coronary artery
Rodrigo Zea-Vera1, Sainath Asokan2, Rohan M Shah1
1Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Tex.
Insights
Racial disparities exist in coronary artery disease interventions. African American patients were less likely to receive coronary artery bypass grafting and experienced worse outcomes, highlighting a need for further investigation into these disparities.
Area of Science:
- Cardiovascular Medicine
- Health Services Research
- Health Disparities
Background:
- Racial and ethnic disparities in cardiovascular disease intervention strategies are a significant concern.
- Understanding treatment patterns and outcomes across different racial/ethnic groups is crucial for addressing inequities.
Purpose of the Study:
- To investigate trends and outcomes of coronary artery disease (CAD) treatment choices, specifically coronary artery bypass grafting (CABG) versus percutaneous coronary intervention (PCI).
- To analyze these trends stratified by race/ethnicity using a large national inpatient database.
Main Methods:
- A retrospective analysis of the National Inpatient Sample (NIS) database from 2002 to 2017.
- Inclusion of patients undergoing isolated CABG or PCI, with outcomes stratified by race/ethnicity (White, African American, Hispanic, Asian).
- Multivariable logistic regression was used to assess associations between race/ethnicity and treatment choice, in-hospital mortality, and costs, adjusting for confounders.
Main Results:
- Over 9.6 million procedures were analyzed. African American patients, compared to White patients, were younger, had higher rates of Medicaid insurance, and more comorbidities.
- After risk adjustment, African Americans were significantly less likely to undergo CABG (OR, 0.76) and had higher risk-adjusted mortality after CABG (OR, 1.09).
- No significant difference in mortality was observed after PCI. African Americans incurred higher hospitalization costs for both CABG and PCI.
Conclusions:
- Significant racial/ethnic differences exist in the utilization and outcomes of coronary artery disease interventions.
- African American patients face lower odds of receiving CABG and experience worse outcomes, alongside higher costs.
- Further research is essential to elucidate the reasons behind these disparities and to develop strategies for equitable care.
Objective:
Studies have noted racial/ethnic disparities in coronary artery disease intervention strategies. We investigated trends and outcomes of coronary artery disease treatment choice (coronary artery bypass grafting or percutaneous coronary intervention) stratified by race/ethnicity.
Methods:
We queried the National Inpatient Sample for patients who underwent isolated coronary artery bypass grafting or percutaneous coronary intervention (2002-2017). Outcomes were stratified by race/ethnicity (White, African American, Hispanic, Asian). Multivariable logistic regression evaluated associations between race/ethnicity and receiving coronary artery bypass grafting versus percutaneous coronary intervention, in-hospital mortality, and costs.
Results:
Over the 15-year period, 2,426,917 isolated coronary artery bypass grafting surgeries and 7,184,515 percutaneous coronary interventions were performed. Compared with White patients, African American patients were younger (62 [interquartile range, 53-70] vs 66 [interquartile range, 57-75] years), were more likely to have Medicaid insurance (12.2% vs 4.4%), and had more comorbidities (Charlson-Deyo index, 1.9 ± 1.6 vs 1.7 ± 1.6) (all P < .01). After adjustment for patient comorbidities, presence of acute myocardial infarction, insurance status, and geography, African Americans were the least likely of all racial/ethnic groups to undergo coronary artery bypass grafting (odds ratio, 0.76; P < .01), a consistent trend throughout the study. African American patients had higher risk-adjusted mortality after coronary artery bypass grafting (odds ratio, 1.09; P < .01). Race/ethnicity was not associated with increased mortality after percutaneous coronary intervention. African American patients had higher hospitalization costs for coronary artery bypass grafting (+$5816; P < .01) and percutaneous coronary intervention (+$856; P < .01) after controlling for confounders.
Conclusions:
In this contemporary national analysis, risk-adjusted frequency of coronary artery bypass grafting versus percutaneous coronary intervention for coronary artery disease differed by race/ethnicity. African American patients had lower odds of undergoing coronary artery bypass grafting and worse outcomes. Reasons for these differences merit further investigation to identify opportunities to reduce potential disparities.
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