Related Experiment Video
Updated: Oct 1, 2025

Laparoscopic Anterior Right Hepatectomy: A Single-Center Experience
Published on: December 4, 2023
Characteristics of Acute Appendicitis before and during the COVID-19 Pandemic: Single Center Experience
A Bosak Veršić1, M Šestan2, I Ćepić3
1Pediatric Surgery Department, University Hospital Rijeka, Rijeka 51000, Croatia.
Insights
The COVID-19 pandemic did not significantly increase complicated appendicitis rates. Researchers found no significant difference in perforated appendicitis between pre-pandemic and pandemic periods, emphasizing accessible emergency care.
Area of Science:
- General Surgery
- Infectious Diseases
- Epidemiology
Background:
- Acute appendicitis is a common surgical emergency.
- The COVID-19 pandemic may have caused delays in emergency department presentations.
- Investigating pandemic's impact on appendicitis complications is crucial.
Purpose of the Study:
- To determine if the COVID-19 pandemic led to increased complicated appendicitis due to delayed patient presentation.
- To compare the incidence of perforated appendicitis before and during the COVID-19 pandemic.
Main Methods:
- Retrospective study of 427 patients undergoing appendicitis surgery (June 2019 - November 2020).
- Patients divided into pre-COVID-19 (n=240) and COVID-19 (n=187) groups.
- Primary outcome: comparison of perforated appendicitis rates between the two groups.
Main Results:
- Overall, 84 patients (19.67%) had perforated appendicitis.
- Perforated appendicitis rates were 17.08% pre-COVID-19 and 22.99% during the COVID-19 era.
- A weak, non-significant trend (p=0.085) was observed.
Conclusions:
- No significant difference in acute appendicitis complications was found between pre-COVID-19 and COVID-19 periods.
- The study highlights the continued need for accessible emergent medical care.
- Findings suggest pandemic-related delays did not significantly worsen appendicitis outcomes in this cohort.
Abstract:
The aim of the study was to investigate whether the COVID-19 pandemic caused an increased incidence of complicated appendicitis due to the late presentation when compared to the pre-COVID-19 period. Summary Background Data. Acute appendicitis is one of the most common surgical emergencies. During the coronavirus-19 (COVID-19) pandemic, there has been a reported delay in the presentation of some urgencies to the emergency hospital departments. Methods. A total of 427 patients who underwent surgical treatment due to suspected acute appendicitis from June 2019 to November 2020 were retrospectively included in this study. The patients were divided into two groups: the first (pre-COVID-19) group consisted of patients who had surgery before the onset of COVID-19 pandemic (n = 240), while the second (COVID-19) group consisted of those who were operated during the COVID-19 pandemic (n = 187). The primary outcome of the study was to compare the incidence of perforated appendicitis before and during the onset of COVID-19. Results. Overall, 84 patients (19.67%) were diagnosed with perforated appendicitis. We found a weak significance (p=0.085) in the rate of perforated appendicitis between the pre-COVID-19 (17.08%) and the COVID-19 era (22.99%). Conclusions. We did not observe any significant difference in the complications of acute appendicitis before and during the COVID-19 pandemic in a university hospital in Rijeka. An emergent medical care should always be accessible.
Related Concept Videos
Appendicitis-I: Introduction
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Appendicitis-II: Diagnostic Studies and Management
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Acute Pancreatitis II: Clinical Manifestations and Management
Acute Pyelonephritis I: Introduction
Acute Pancreatitis I: Introduction
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Acute Pyelonephritis II: Diagnostic Studies and Management

