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Related Concept Videos

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Acute Pyelonephritis I: Introduction

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Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
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Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
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The phylum Tenericutes, which includes the single class Mollicutes, comprises bacteria that lack cell walls. The term "Mollicutes" derives from the Latin word mollis, meaning "soft." These organisms are among the smallest known and are commonly referred to as mycoplasmas due to the prominence of the genus Mycoplasma, which includes well-known human pathogens. Despite their inability to stain gram-positively (a result of their lack of cell walls), mycoplasmas are phylogenetically related to the...
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Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
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Acute Pyelonephritis II: Diagnostic Studies and Management01:28

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Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
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Pulmonary Tuberculosis IV01:26

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Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
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Related Experiment Video

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Fulminant Necrotizing Pyomyositis Tropicans.

Snehasis Das1, Oseen Shaikh1, Naveen Kumar Gaur1

  • 1Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, IND.

Cureus
|March 7, 2022
PubMed
Summary

Fulminant necrotizing pyomyositis, a rare invasive muscle infection, occurred in an immunocompetent teen. This case, caused by Escherichia coli, highlights a unique presentation leading to fatal septic shock.

Keywords:
antibioticsdebridementimmunocompetentpyomyositisseptic shock

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Area of Science:

  • Infectious Diseases
  • Bacteriology
  • Critical Care Medicine

Background:

  • Pyomyositis tropicans is typically a bacterial infection of striated muscle, often caused by Staphylococcus aureus or Streptococcus.
  • It predominantly affects immunocompromised individuals, presenting as a purulent invasive process.

Observation:

  • A 16-year-old immunocompetent patient presented with symptoms suggestive of extensive intramuscular abdominal wall abscess.
  • Imaging confirmed significant abscess formation, necessitating surgical intervention on the lateral thoracic wall.

Findings:

  • The causative organism identified through cultures was Escherichia coli, an unusual pathogen for this presentation.
  • Despite surgical debridement, the patient developed irreversible septic shock, resulting in a fatality.

Implications:

  • This case represents the first reported instance of fulminant necrotizing pyomyositis in an immunocompetent host due to Escherichia coli.
  • It underscores the potential for severe, rapidly progressing infections even in immunocompetent individuals and expands the known spectrum of pyomyositis tropicans.
  • Highlights the critical need for prompt diagnosis and aggressive management of invasive bacterial infections.