Related Experiment Video
Updated: Oct 1, 2025
08:05
Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
Published on: December 19, 2020
14.4K
COVID-19's impact on lung tissue: A case report
Connor Crudeli1, Brian Zilberman2, Jennifer Williams2
1Cooper Medical School of Rowan University, 401 Broadway, Camden, NJ 08103, USA.
International Journal of Surgery Case Reports
|March 7, 2022
Summary
This case study highlights a COVID-19 patient who developed empyema. Thoracic surgery proved safe, and findings suggest reconsidering anticoagulation and tocilizumab guidelines for COVID-19 patients with empyema.
Area of Science:
- Pulmonology
- Infectious Diseases
- Thoracic Surgery
Background:
- Limited information exists on managing empyema in COVID-19 patients.
- Established empyema guidelines predate COVID-19, necessitating updated evidence.
- This case presents a COVID-19 patient with empyema from a tertiary care institution.
Observation:
- A 59-year-old male with COPD and hypertension presented with COVID pneumonia.
- The patient developed bacterial pneumonia and loculated pleural empyema despite tocilizumab treatment.
- A muscle-sparing thoracotomy and decortication were performed on day 57, leading to recovery.
Findings:
- COVID-19 associated pulmonary microthrombi can cause vascular dysfunction and hypoxia.
- Superimposed bacterial pneumonia raises concerns regarding tocilizumab use in COVID-19.
- The patient required anticoagulation due to microvascular occlusions.
Implications:
- Thoracic surgery is safe for patients and practitioners during the pandemic.
- Current guidelines for empyema management may require revision for COVID-19 patients.
- Further research is needed on anticoagulation strategies for COVID-19-related coagulopathies.
Related Concept Videos
01:20COPD: Pathogenesis and Clinical Features
659
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
659
01:20Chronic Obstructive Pulmonary Disease-II: Pathophysiology
3.2K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Chronic Inflammation
3.2K
01:29Pneumonia II: Pathophysiology
851
The pathophysiology of pneumonia involves the following steps:
851
01:22Chronic Obstructive Pulmonary Disease
1.5K
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
1.5K
01:20Chronic Obstructive Pulmonary Disease-I: Introduction
3.0K
Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
3.0K
01:27Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
2.6K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Medical History
2.6K