Natural Nanoclay-Based Silver-Phosphomolybdic Acid Composite with a Dual Antimicrobial Effect
Andrei A Novikov1, Adeliya R Sayfutdinova1, Maksim V Gorbachevskii1
1Physical and Colloid Chemistry Department, Gubkin University, 65/1 Leninsky Prospect, Moscow 119991, Russian Federation.
ACS Omega
|March 7, 2022
Summary
This study presents a novel antibiotic-free nanocomposite using halloysite, silver nanoparticles, and phosphomolybdic acid. This material effectively inhibits the growth of resistant bacteria, offering a new strategy for antimicrobial coatings.
Area of Science:
- Materials Science
- Nanotechnology
- Microbiology
Background:
- Rising antibiotic resistance and hospital-acquired infections necessitate new antibacterial strategies.
- Existing treatments face challenges due to microbial resistance.
- Development of antibiotic-free solutions is crucial for public health.
Purpose of the Study:
- To develop a novel antibiotic-free antibacterial halloysite-based nanocomposite.
- To utilize silver nanoparticles and phosphomolybdic acid as biocides.
- To create components for smart antimicrobial coatings.
Main Methods:
- Fabrication of a halloysite-based nanocomposite incorporating silver nanoparticles and phosphomolybdic acid.
- Characterization using energy-dispersive X-ray fluorescence spectroscopy and transmission electron microscopy.
- Assessment of phosphomolybdic acid release via UV-vis spectroscopy.
Main Results:
- The developed nanocomposite demonstrated broad-spectrum antibacterial properties.
- Complete inhibition of *Staphylococcus aureus* and *Pseudomonas aeruginosa* at 0.5 g/L.
- Complete inhibition of *Acinetobacter baumannii* at 0.25 g/L.
Conclusions:
- The antibiotic-free halloysite-silver-phosphomolybdic acid nanocomposite shows significant potential as an antimicrobial agent.
- This material offers a promising alternative to conventional antibiotics for combating resistant bacteria.
- The findings support the use of this nanocomposite in smart antimicrobial coatings.
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