Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Ribosome Profiling

Ribosome Profiling

Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

[Comparative study on effectiveness of bioinductive patch-augmented arthroscopic rotator cuff repair].

Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery·2026

Same author

Engineering chitosan-functionalized liposomes for targeted drug delivery and biomedical applications.

International journal of biological macromolecules·2026

Same author

Unlocking the potential of atractylenolide II: Mitigating non-alcoholic fatty liver disease through farnesoid X receptor-endoplasmic reticulum stress interplay.

Journal of pharmaceutical analysis·2026

Same author

Biomarkers.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025

Same author

Biomarkers.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025

Same author

Biomarkers.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2025

Search research articles

Related Experiment Video

Updated: Oct 1, 2025

Obtaining High-Quality Transcriptome Data from Cereal Seeds by a Modified Method for Gene Expression Profiling

Obtaining High-Quality Transcriptome Data from Cereal Seeds by a Modified Method for Gene Expression Profiling

Published on: May 21, 2020

Transcriptomics analysis of cashmere fineness functional genes.

Yuting Qin¹, Yanan Xu¹, Yu Zhang¹

¹College of Animal Science and Veterinary Medicine, Shenyang Agricultural University, Shenyang, China.

Animal Biotechnology

|March 7, 2022

Summary

Researchers identified 16 key genes potentially regulating cashmere fineness in Liaoning cashmere goats (LCG). This study used RNA-sequencing to analyze gene expression differences between coarse and fine cashmere LCG skin samples.

Keywords:

Cashmere fineness Liaoning cashmere goat RNA-seq genomics transcriptomics

More Related Videos

Identification of Key Factors Regulating Self-renewal and Differentiation in EML Hematopoietic Precursor Cells by RNA-sequencing Analysis

Identification of Key Factors Regulating Self-renewal and Differentiation in EML Hematopoietic Precursor Cells by RNA-sequencing Analysis

Published on: November 11, 2014

Identification of Alternative Splicing and Polyadenylation in RNA-seq Data

Identification of Alternative Splicing and Polyadenylation in RNA-seq Data

Published on: June 24, 2021

Related Experiment Videos

Last Updated: Oct 1, 2025

Obtaining High-Quality Transcriptome Data from Cereal Seeds by a Modified Method for Gene Expression Profiling

Obtaining High-Quality Transcriptome Data from Cereal Seeds by a Modified Method for Gene Expression Profiling

Published on: May 21, 2020

Identification of Key Factors Regulating Self-renewal and Differentiation in EML Hematopoietic Precursor Cells by RNA-sequencing Analysis

Identification of Key Factors Regulating Self-renewal and Differentiation in EML Hematopoietic Precursor Cells by RNA-sequencing Analysis

Published on: November 11, 2014

Identification of Alternative Splicing and Polyadenylation in RNA-seq Data

Identification of Alternative Splicing and Polyadenylation in RNA-seq Data

Published on: June 24, 2021

Area of Science:

Animal Genetics
Molecular Biology
Textile Science

Background:

Liaoning cashmere goats (LCG) are a prized Chinese breed, but improving cashmere fineness is crucial for quality.
Cashmere fineness is a key economic trait, necessitating genetic and molecular investigations.
Understanding gene expression is vital for improving livestock traits and managing diseases.

Purpose of the Study:

To identify genes associated with cashmere fineness in LCG.
To analyze differential gene expression between coarse and fine cashmere LCG skin.
To explore the molecular pathways involved in cashmere fineness regulation.

Main Methods:

RNA-sequencing (RNA-seq) of skin samples from coarse and fine LCG.
Differential gene expression analysis to identify significant gene expression changes.
Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis.

Main Results:

A total of 427 differentially expressed genes were identified between coarse and fine cashmere LCG.
16 genes showed significant expression differences and are proposed as potential regulators of cashmere fineness.
Enrichment analysis indicated involvement of immune response, MHC protein complex, heme binding, transplant-versus-host disease, and allograft rejection pathways.

Conclusions:

The identified 16 genes may play a regulatory role in determining cashmere fineness in LCG.
Immune-related pathways are significantly associated with variations in cashmere fineness.
Further research into these genes and pathways could lead to breeding strategies for enhanced cashmere quality.