Related Experiment Video
Updated: Oct 1, 2025

Author Spotlight: Exploring Huotan Jiedu Tongluo Decoction as an Antihypertensive Drug
Published on: May 17, 2024
Sex Differences in the Prevalence, Outcomes and Management of Hypertension
Paul J Connelly1, Gemma Currie1, Christian Delles2
1Institute of Cardiovascular and Medical Sciences, University of Glasgow, 126 University Place, Glasgow, G12 8TA, UK.
Purpose Of Review:
To review recent data on sex differences in the prevalence, outcomes and management of hypertension.
Recent Findings:
Although hypertension is overall more common in males, females experience a much sharper incline in blood pressure from the third decade of life and consequently the prevalence of hypertension accelerates comparatively with age. Mechanisms responsible for these blood pressure trajectories may include the sustained vascular influence of hypertensive disorders of pregnancy, interactions between the renin-angiotensin-aldosterone system and sex hormones or even psychosocial gendered factors such as socioeconomic deprivation. Moreover, the impact of hypertension is not uniform and females are at higher risk of developing a multitude of adverse cardiovascular outcomes at lower blood pressure thresholds. Blood pressure is a sexually dimorphic trait and although significant differences exist in the prevalence, pathophysiology and outcomes of hypertension in males and females, limited data exist to support sex-specific blood pressure targets.
Related Concept Videos
Hypertension III: Clinical Manifestations and Diagnostic Studies
Hypertension I: Introduction
Factors affecting Blood pressure
Physiological Factors:
Hypertension and Regulation of Blood Pressure
Alterations in Blood Pressure
Hypertension (High blood pressure)
Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart...
Hypertension V: Nursing Management

