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Updated: Oct 1, 2025

Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications
Published on: April 30, 2014
Surgical Considerations in Revision Anterior Cruciate Ligament Reconstruction
Abstract:
Revision anterior cruciate ligament reconstruction (rACLR) procedures are often technically and intellectually challenging. However, with careful preoperative evaluation and planning, the likelihood of success can be maximized. Understanding the various etiologies of and contributors to primary ACLR failure can guide the surgical plan in terms of whether concomitant procedures are needed. Although successful outcomes have been reported with both one-stage and two-stage rACLRs, appropriate patient selection is important. Overall, clinical outcomes including patient-reported outcomes, graft failure rates, and return to sport are worse after rACLR compared with primary ACLR. It is important to review the preoperative evaluation, surgical considerations, and outcomes of rACLR.
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