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Related Concept Videos

The Pituitary Gland01:17

The Pituitary Gland

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The pituitary is a small endocrine organ in the sphenoid bone under the hypothalamus. Primarily, the pituitary in adults has two distinct anatomical and functional regions— the anterior and posterior lobes. During human fetal development, a third pituitary gland region called the pars intermedia atrophies and disappears. However, some of its cells migrate and exist adjacent to the anterior pituitary in adults.
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Hormones of the Pituitary Gland01:27

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The small, pea-sized pituitary gland is located at the base of the brain. It is crucial in regulating various bodily functions, from growth to reproduction. The gland is divided into the anterior lobe and the posterior lobe. The secretory cell clusters in the pars distalis of the anterior pituitary lobe are controlled by hypothalamic regulators and synthesize six primary hormones.
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Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
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Updated: Oct 1, 2025

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
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Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

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Pediatric Pituitary Surgery.

Peter J Madsen1, Shih-Shan Lang2, Nithin D Adappa3

  • 1Division of Neurosurgery, Children's Hospital of Philadelphia, Wood Building, 3401 Civic Center Boulevard, Philadelphia, PA 19104, USA.

Otolaryngologic Clinics of North America
|March 8, 2022
PubMed
Summary
This summary is machine-generated.

Pediatric pituitary and sellar region lesions can be surgically managed with advanced techniques, despite anatomical challenges. This review covers common conditions, surgical approaches, and future directions for treating these pediatric brain tumors.

Keywords:
CraniopharyngiomaEndonasalPediatricRathke cleft cystSkull base

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Area of Science:

  • Pediatric Neurosurgery
  • Endocrinology
  • Ophthalmology

Background:

  • Pituitary and sellar region lesions present diverse pathologies in children.
  • Surgical intervention for these lesions is feasible due to technological advancements.
  • Age-dependent anatomical constraints pose unique challenges in pediatric skull base surgery.

Purpose of the Study:

  • To review common pathologic conditions affecting the pediatric pituitary and sellar region.
  • To discuss perioperative management strategies for pediatric patients with these lesions.
  • To outline surgical techniques for lesion resection and pediatric skull base repair.

Main Methods:

  • Comprehensive literature review of pediatric pituitary and sellar region lesions.
  • Analysis of current surgical technologies and techniques.
  • Discussion of perioperative care and skull base reconstruction methods.

Main Results:

  • Identification of common pediatric pituitary and sellar pathologies.
  • Description of advanced surgical approaches enabling biopsy and resection.
  • Highlighting of techniques for pediatric skull base repair.

Conclusions:

  • Surgical management of pediatric pituitary and sellar lesions is advancing.
  • Multidisciplinary approaches are crucial for optimal patient outcomes.
  • Ongoing research will further refine surgical techniques and patient care.