Related Experiment Video For Breast density
Updated: Oct 1, 2025

Ex Vivo Treatment Response of Primary Tumors and/or Associated Metastases for Preclinical and Clinical Development of Therapeutics
Published on: October 2, 2014
The conundrum of breast density; guidance for healthcare providers
Sandra Dayaratna1, Rebecca Jackson1
1Thomas Jefferson University Hospital, Department of Ob-Gyn, 833 Chestnut Street, Philadelphia, PA, 19107, USA.
Abstract:
A finding of dense breasts on mammogram decreases the sensitivity of mammogram and increases a woman's risk of breast cancer. Supplemental screening can increase breast cancer detection in women with dense breasts, but caries a risk of increased false-positive test results. There are currently no clear guidelines for providers or patients on recommendations for supplemental screening after a mammogram finding of heterogeneously or extremely dense breasts on mammography. In addition, there is currently great variation in communication and management of breast density amongst physicians and other licensed providers. Women at higher risk for developing breast cancer would benefit most from supplemental screening. Standardizing recommendations and implementation of risk-based decision-making using a validated calculator would allow for earlier detection of breast cancer, clear guidance for providers, and ensure equitable care for patients.
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