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Metastatic Neoplasms to the Vulva-A Review
Alexis Heller1, Daniel Breitner1, Bernadette Cracchiolo2
1Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Introduction:
Metastatic neoplasms to the vulva are rare and can pose a diagnostic dilemma. As identification of the primary site can influence patient treatment and prognosis, correct diagnosis is important.
Methods:
PubMed was searched for applicable publications using the terms vulva, vulvar neoplasms, metastasis, and vulvar metastasis.
Results:
Most neoplasms metastatic to the vulva originate from other genital sources; however, extragenital primary neoplasms can also metastasize to the vulva. Vulvar metastases often occur in the setting of widespread disease.
Conclusions:
It is important to consider biopsy for appropriate histologic and immunohistochemical studies, as well as consider patient history to establish the primary site of metastatic lesions to the vulva, allowing optimal therapy.
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